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Leptin promotes fetal lung maturity and upregulates SP-A expression in pulmonary alveoli type-II epi...

Leptin promotes fetal lung maturity and upregulates SP-A expression in pulmonary alveoli type-II epi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1427370302

Leptin promotes fetal lung maturity and upregulates SP-A expression in pulmonary alveoli type-II epithelial cells involving TTF-1 activation

About this item

Full title

Leptin promotes fetal lung maturity and upregulates SP-A expression in pulmonary alveoli type-II epithelial cells involving TTF-1 activation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-07, Vol.8 (7), p.e69297

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The placental hormone leptin has important functions in fetal and neonatal growth, and prevents depressed respiration in leptin-deficient mice. The effect of leptin on respiratory distress suffered by low birth weight and premature infants has been studied. However, it is unclear how leptin enhances lung maturity in the fetus and ameliorates neonat...

Alternative Titles

Full title

Leptin promotes fetal lung maturity and upregulates SP-A expression in pulmonary alveoli type-II epithelial cells involving TTF-1 activation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1427370302

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1427370302

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0069297

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