Behavioral characterization of A53T mice reveals early and late stage deficits related to Parkinson'...
Behavioral characterization of A53T mice reveals early and late stage deficits related to Parkinson's disease
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Parkinson's disease (PD) pathology is characterized by the formation of intra-neuronal inclusions called Lewy bodies, which are comprised of alpha-synuclein (α-syn). Duplication, triplication or genetic mutations in α-syn (A53T, A30P and E46K) are linked to autosomal dominant PD; thus implicating its role in the pathogenesis of PD. In both PD patie...
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Behavioral characterization of A53T mice reveals early and late stage deficits related to Parkinson's disease
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TN_cdi_plos_journals_1430168870
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1430168870
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0070274
