Clonal Expansion Analysis of Transposon Insertions by High-Throughput Sequencing Identifies Candidat...
Clonal Expansion Analysis of Transposon Insertions by High-Throughput Sequencing Identifies Candidate Cancer Genes in a PiggyBac Mutagenesis Screen
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Somatic transposon mutagenesis in mice is an efficient strategy to investigate the genetic mechanisms of tumorigenesis. The identification of tumor driving transposon insertions traditionally requires the generation of large tumor cohorts to obtain information about common insertion sites. Tumor driving insertions are also characterized by their cl...
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Clonal Expansion Analysis of Transposon Insertions by High-Throughput Sequencing Identifies Candidate Cancer Genes in a PiggyBac Mutagenesis Screen
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TN_cdi_plos_journals_1430170891
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1430170891
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0072338
