Log in to save to my catalogue

Soluble variants of human recombinant glutaminyl cyclase

Soluble variants of human recombinant glutaminyl cyclase

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1430436697

Soluble variants of human recombinant glutaminyl cyclase

About this item

Full title

Soluble variants of human recombinant glutaminyl cyclase

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-08, Vol.8 (8), p.e71657-e71657

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Recombinant human Glutaminyl Cyclase expressed in E. coli is produced as inclusion bodies. Lack of glycosylation is the main origin of its accumulation in insoluble aggregates. Mutation of single isolated hydrophobic amino acids into negative amino acids was not able to circumvent inclusion bodies formation. On the contrary, substitution with carbo...

Alternative Titles

Full title

Soluble variants of human recombinant glutaminyl cyclase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1430436697

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1430436697

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0071657

How to access this item