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SORLA-mediated trafficking of TrkB enhances the response of neurons to BDNF

SORLA-mediated trafficking of TrkB enhances the response of neurons to BDNF

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1430785992

SORLA-mediated trafficking of TrkB enhances the response of neurons to BDNF

About this item

Full title

SORLA-mediated trafficking of TrkB enhances the response of neurons to BDNF

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-08, Vol.8 (8), p.e72164-e72164

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Stimulation of neurons with brain-derived neurotrophic factor (BDNF) results in robust induction of SORLA, an intracellular sorting receptor of the VPS10P domain receptor gene family. However, the relevance of SORLA for BDNF-induced neuronal responses has not previously been investigated. We now demonstrate that SORLA is a sorting factor for the tr...

Alternative Titles

Full title

SORLA-mediated trafficking of TrkB enhances the response of neurons to BDNF

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1430785992

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1430785992

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0072164

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