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Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency

Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1433049610

Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency

About this item

Full title

Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-09, Vol.8 (9), p.e74950-e74950

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

It has been demonstrated for some cancers that the frequency of somatic oncogenic mutations may vary in ancestral populations. To determine whether key driver alterations might occur at different frequencies in colorectal cancer, we applied a high-throughput genotyping platform (OncoMap) to query 385 mutations across 33 known cancer genes in colore...

Alternative Titles

Full title

Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1433049610

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1433049610

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0074950

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