Ginkgolide B reduces LOX-1 expression by inhibiting Akt phosphorylation and increasing Sirt1 express...
Ginkgolide B reduces LOX-1 expression by inhibiting Akt phosphorylation and increasing Sirt1 expression in oxidized LDL-stimulated human umbilical vein endothelial cells
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Oxidized low-density lipoprotein (ox-LDL) is an important risk factor in the development of atherosclerosis. LOX-1, a lectin-like receptor for ox-LDL, is present primarily on endothelial cells and upregulated by ox-LDL, tumor necrosis factor a, shear stress, and cytokines in atherosclerosis. Recent studies demonstrated that ginkgolide B, a platelet...
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Ginkgolide B reduces LOX-1 expression by inhibiting Akt phosphorylation and increasing Sirt1 expression in oxidized LDL-stimulated human umbilical vein endothelial cells
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TN_cdi_plos_journals_1433331988
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1433331988
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0074769
