NSD1 Mitigates Caspase-1 Activation by Listeriolysin O in Macrophages
NSD1 Mitigates Caspase-1 Activation by Listeriolysin O in Macrophages
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Mammals and plants share pathogen-sensing systems named nod-like receptors (NLRs). Some NLRs form the inflammasome, a protein scaffold that regulates the secretion of interleukin (IL)-1β and IL-18 by cleaving catalytically inactive substrates into mature cytokines. Here, we show an immune conservation between plant and mammalian NLRs and demonstrat...
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Full title
NSD1 Mitigates Caspase-1 Activation by Listeriolysin O in Macrophages
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TN_cdi_plos_journals_1433799390
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1433799390
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0075911
