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Localization of HPV-18 E2 at mitochondrial membranes induces ROS release and modulates host cell met...

Localization of HPV-18 E2 at mitochondrial membranes induces ROS release and modulates host cell met...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1435972298

Localization of HPV-18 E2 at mitochondrial membranes induces ROS release and modulates host cell metabolism

About this item

Full title

Localization of HPV-18 E2 at mitochondrial membranes induces ROS release and modulates host cell metabolism

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-09, Vol.8 (9), p.e75625

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Papillomavirus E2 proteins are predominantly retained in the nuclei of infected cells, but oncogenic (high-risk) HPV-18 and 16 E2 can shuttle between the host nucleus and cytoplasm. We show here that cytoplasmic HPV-18 E2 localizes to mitochondrial membranes, and independent mass spectrometry analyses of the E2 interactome revealed association to t...

Alternative Titles

Full title

Localization of HPV-18 E2 at mitochondrial membranes induces ROS release and modulates host cell metabolism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1435972298

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1435972298

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0075625

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