Localization of HPV-18 E2 at mitochondrial membranes induces ROS release and modulates host cell met...
Localization of HPV-18 E2 at mitochondrial membranes induces ROS release and modulates host cell metabolism
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Papillomavirus E2 proteins are predominantly retained in the nuclei of infected cells, but oncogenic (high-risk) HPV-18 and 16 E2 can shuttle between the host nucleus and cytoplasm. We show here that cytoplasmic HPV-18 E2 localizes to mitochondrial membranes, and independent mass spectrometry analyses of the E2 interactome revealed association to t...
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Full title
Localization of HPV-18 E2 at mitochondrial membranes induces ROS release and modulates host cell metabolism
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TN_cdi_plos_journals_1435972298
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1435972298
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0075625
