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Therapeutic potential of the translation inhibitor silvestrol in hepatocellular cancer

Therapeutic potential of the translation inhibitor silvestrol in hepatocellular cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1437157322

Therapeutic potential of the translation inhibitor silvestrol in hepatocellular cancer

About this item

Full title

Therapeutic potential of the translation inhibitor silvestrol in hepatocellular cancer

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-09, Vol.8 (9), p.e76136

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Although hepatocellular cancers (HCC) frequently arise in the setting of fibrosis and a hepatic regenerative response requiring new cell growth, therapeutic strategies for these cancers have not targeted protein synthesis. Silvestrol, a rocaglate isolated from Aglaiafoveolata, can inhibit protein synthesis by modulating the initiation of translatio...

Alternative Titles

Full title

Therapeutic potential of the translation inhibitor silvestrol in hepatocellular cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1437157322

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1437157322

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0076136

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