Therapeutic potential of the translation inhibitor silvestrol in hepatocellular cancer
Therapeutic potential of the translation inhibitor silvestrol in hepatocellular cancer
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Although hepatocellular cancers (HCC) frequently arise in the setting of fibrosis and a hepatic regenerative response requiring new cell growth, therapeutic strategies for these cancers have not targeted protein synthesis. Silvestrol, a rocaglate isolated from Aglaiafoveolata, can inhibit protein synthesis by modulating the initiation of translatio...
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Full title
Therapeutic potential of the translation inhibitor silvestrol in hepatocellular cancer
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TN_cdi_plos_journals_1437157322
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1437157322
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0076136