Intelligently targeted drug delivery and enhanced antitumor effect by gelatinase-responsive nanopart...
Intelligently targeted drug delivery and enhanced antitumor effect by gelatinase-responsive nanoparticles
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Author / Creator
Li, Rutian , Wu, Wei , Liu, Qin , Wu, Puyuan , Xie, Li , Zhu, Zhenshu , Yang, Mi , Qian, Xiaoping , Ding, Yin , Yu, Lixia , Jiang, Xiqun , Guan, Wenxian and Liu, Baorui
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The matrix metalloproteinase (MMP) 2/9, also known as collagenases IV and gelatinases A/B, play a key role in cancer invasion and metastasis. However, the clinical trials of the MMP inhibitors (MMPIs) ended up with disappointing results. In this paper, we synthesized a gelatinase-responsive copolymer (mPEG-PCL) by inserting a gelatinase cleavable p...
Alternative Titles
Full title
Intelligently targeted drug delivery and enhanced antitumor effect by gelatinase-responsive nanoparticles
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Record Identifier
TN_cdi_plos_journals_1440972809
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1440972809
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0069643
