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Klotho sensitivity of the neuronal excitatory amino acid transporters EAAT3 and EAAT4

Klotho sensitivity of the neuronal excitatory amino acid transporters EAAT3 and EAAT4

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1440997623

Klotho sensitivity of the neuronal excitatory amino acid transporters EAAT3 and EAAT4

About this item

Full title

Klotho sensitivity of the neuronal excitatory amino acid transporters EAAT3 and EAAT4

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-07, Vol.8 (7), p.e70988-e70988

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Klotho, a transmembrane protein, which can be cleaved off as β-glucuronidase and hormone, is released in both, kidney and choroid plexus and encountered in blood and cerebrospinal fluid. Klotho deficiency leads to early appearance of age-related disorders and premature death. Klotho may modify transport by inhibiting 1,25(OH)2D3 formation or by dir...

Alternative Titles

Full title

Klotho sensitivity of the neuronal excitatory amino acid transporters EAAT3 and EAAT4

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1440997623

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1440997623

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0070988

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