VAPB/ALS8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caen...
VAPB/ALS8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis elegans
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Mutations in VAPB/ALS8 are associated with amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), two motor neuron diseases that often include alterations in energy metabolism. We have shown that C. elegans and Drosophila neurons secrete a cleavage product of VAPB, the N-terminal major sperm protein domain (vMSP). Secreted vMSPs sig...
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VAPB/ALS8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis elegans
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TN_cdi_plos_journals_1442463477
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1442463477
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1553-7404,1553-7390
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1553-7404
DOI
10.1371/journal.pgen.1003738
