The tumor suppressor gene, RASSF1A, is essential for protection against inflammation -induced injury
The tumor suppressor gene, RASSF1A, is essential for protection against inflammation -induced injury
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Author / Creator
Gordon, Marilyn , El-Kalla, Mohamed , Zhao, Yuewen , Fiteih, Yahya , Law, Jennifer , Volodko, Natalia , Anwar-Mohamed, Anwar , Mohamed, Anwar , El-Kadi, Ayman O S , Liu, Lei , Odenbach, Jeff , Thiesen, Aducio , Onyskiw, Christina , Ghazaleh, Haya Abu , Park, Jikyoung , Lee, Sean Bong , Yu, Victor C , Fernandez-Patron, Carlos , Alexander, R Todd , Wine, Eytan and Baksh, Shairaz
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Ras association domain family protein 1A (RASSF1A) is a tumor suppressor gene silenced in cancer. Here we report that RASSF1A is a novel regulator of intestinal inflammation as Rassf1a(+/-) , Rassf1a(-/-) and an intestinal epithelial cell specific knockout mouse (Rassf1a (IEC-KO) ) rapidly became sick following dextran sulphate sodium (DSS) adminis...
Alternative Titles
Full title
The tumor suppressor gene, RASSF1A, is essential for protection against inflammation -induced injury
Authors, Artists and Contributors
Author / Creator
El-Kalla, Mohamed
Zhao, Yuewen
Fiteih, Yahya
Law, Jennifer
Volodko, Natalia
Anwar-Mohamed, Anwar
Mohamed, Anwar
El-Kadi, Ayman O S
Liu, Lei
Odenbach, Jeff
Thiesen, Aducio
Onyskiw, Christina
Ghazaleh, Haya Abu
Park, Jikyoung
Lee, Sean Bong
Yu, Victor C
Fernandez-Patron, Carlos
Alexander, R Todd
Wine, Eytan
Baksh, Shairaz
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1442465901
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1442465901
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0075483
