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Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage ph...

Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage ph...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1443691251

Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypes

About this item

Full title

Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypes

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-10, Vol.8 (10), p.e78045-e78045

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Macrophages (MΦ) play an essential role in innate immune responses and can either display a pro-inflammatory, classically activated phenotype (M1) or undergo an alternative activation program (M2) promoting immune regulation. M-CSF is used to differentiate monocytes into MΦ and IFN-γ or IL-4+IL-13 to further polarize these cells towards M1 or M2, r...

Alternative Titles

Full title

Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1443691251

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1443691251

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0078045

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