Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage ph...
Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypes
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Macrophages (MΦ) play an essential role in innate immune responses and can either display a pro-inflammatory, classically activated phenotype (M1) or undergo an alternative activation program (M2) promoting immune regulation. M-CSF is used to differentiate monocytes into MΦ and IFN-γ or IL-4+IL-13 to further polarize these cells towards M1 or M2, r...
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Full title
Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypes
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TN_cdi_plos_journals_1443691251
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1443691251
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0078045