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Phase II open-label study to assess efficacy and safety of lenalidomide in combination with cetuxima...

Phase II open-label study to assess efficacy and safety of lenalidomide in combination with cetuxima...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1450016292

Phase II open-label study to assess efficacy and safety of lenalidomide in combination with cetuximab in KRAS-mutant metastatic colorectal cancer

About this item

Full title

Phase II open-label study to assess efficacy and safety of lenalidomide in combination with cetuximab in KRAS-mutant metastatic colorectal cancer

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-11, Vol.8 (11), p.e62264

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

This study aimed to assess the efficacy and safety of combination treatment with lenalidomide and cetuximab in KRAS-mutant metastatic colorectal cancer patients. This was a phase II multicenter, open-label trial comprising a safety lead-in phase (phase IIa) to determine the maximum tolerated dose, and a randomized proof of concept phase (phase IIb)...

Alternative Titles

Full title

Phase II open-label study to assess efficacy and safety of lenalidomide in combination with cetuximab in KRAS-mutant metastatic colorectal cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1450016292

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1450016292

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0062264

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