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Tricyclic antidepressant amitriptyline indirectly increases the proliferation of adult dentate gyrus...

Tricyclic antidepressant amitriptyline indirectly increases the proliferation of adult dentate gyrus...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1459404233

Tricyclic antidepressant amitriptyline indirectly increases the proliferation of adult dentate gyrus-derived neural precursors: an involvement of astrocytes

About this item

Full title

Tricyclic antidepressant amitriptyline indirectly increases the proliferation of adult dentate gyrus-derived neural precursors: an involvement of astrocytes

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-11, Vol.8 (11), p.e79371-e79371

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Antidepressants increase the proliferation of neural precursors in adult dentate gyrus (DG), which is considered to be involved in the therapeutic action of antidepressants. However, the mechanism underlying it remains unclear. By using cultured adult rat DG-derived neural precursors (ADP), we have already shown that antidepressants have no direct...

Alternative Titles

Full title

Tricyclic antidepressant amitriptyline indirectly increases the proliferation of adult dentate gyrus-derived neural precursors: an involvement of astrocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1459404233

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1459404233

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0079371

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