Impact of delay to cryopreservation on RNA integrity and genome-wide expression profiles in resected...
Impact of delay to cryopreservation on RNA integrity and genome-wide expression profiles in resected tumor samples
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The quality of tissue samples and extracted mRNA is a major source of variability in tumor transcriptome analysis using genome-wide expression microarrays. During and immediately after surgical tumor resection, tissues are exposed to metabolic, biochemical and physical stresses characterized as "warm ischemia". Current practice advocates cryopreser...
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Full title
Impact of delay to cryopreservation on RNA integrity and genome-wide expression profiles in resected tumor samples
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TN_cdi_plos_journals_1460160709
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1460160709
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0079826
