Correlation of chromosomal instability, telomere length and telomere maintenance in microsatellite s...
Correlation of chromosomal instability, telomere length and telomere maintenance in microsatellite stable rectal cancer: a molecular subclass of rectal cancer
About this item
Full title
Author / Creator
Boardman, Lisa A , Johnson, Ruth A , Viker, Kimberly B , Hafner, Kari A , Jenkins, Robert B , Riegert-Johnson, Douglas L , Smyrk, Thomas C , Litzelman, Kristin , Seo, Songwon , Gangnon, Ronald E , Engelman, Corinne D , Rider, David N , Vanderboom, Russell J , Thibodeau, Stephen N , Petersen, Gloria M and Skinner, Halcyon G
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Colorectal cancer (CRC) tumor DNA is characterized by chromosomal damage termed chromosomal instability (CIN) and excessively shortened telomeres. Up to 80% of CRC is microsatellite stable (MSS) and is historically considered to be chromosomally unstable (CIN+). However, tumor phenotyping depicts some MSS CRC with little or no genetic changes, thus...
Alternative Titles
Full title
Correlation of chromosomal instability, telomere length and telomere maintenance in microsatellite stable rectal cancer: a molecular subclass of rectal cancer
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1460505152
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1460505152
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0080015
