Functional characteristics of the naked mole rat μ-opioid receptor
Functional characteristics of the naked mole rat μ-opioid receptor
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
While humans and most animals respond to µ-opioid receptor (MOR) agonists with analgesia and decreased aggression, in the naked mole rat (NMR) opioids induce hyperalgesia and severe aggression. Single nucleotide polymorphisms in the human mu-opioid receptor gene (OPRM1) can underlie altered behavioral responses to opioids. Therefore, we hypothesize...
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Full title
Functional characteristics of the naked mole rat μ-opioid receptor
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TN_cdi_plos_journals_1462420037
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1462420037
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0079121
