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A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated protein kinase k...

A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated protein kinase k...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1465241228

A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated protein kinase kinase 4

About this item

Full title

A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated protein kinase kinase 4

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-12, Vol.8 (12), p.e81504-e81504

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Prostate cancer (PCa) is the second highest cause of cancer death in United States males. If the metastatic movement of PCa cells could be inhibited, then mortality from PCa could be greatly reduced. Mitogen-activated protein kinase kinase 4 (MAP2K4) has previously been shown to activate pro-invasion signaling pathways in human PCa. Recognizing tha...

Alternative Titles

Full title

A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated protein kinase kinase 4

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1465241228

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1465241228

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0081504

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