Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis:...
Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects
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Author / Creator
IMSGC , ANZgene , Patsopoulos, Nikolaos A , Barcellos, Lisa F , Hintzen, Rogier Q , Schaefer, Catherine , van Duijn, Cornelia M , Noble, Janelle A , Raj, Towfique , Gourraud, Pierre-Antoine , Stranger, Barbara E , Oksenberg, Jorge , Olsson, Tomas , Taylor, Bruce V , Sawcer, Stephen , Hafler, David A , Carrington, Mary , De Jager, Philip L and de Bakker, Paul I W
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The major histocompatibility complex (MHC) region is strongly associated with multiple sclerosis (MS) susceptibility. HLA-DRB1*15:01 has the strongest effect, and several other alleles have been reported at different levels of validation. Using SNP data from genome-wide studies, we imputed and tested classical alleles and amino acid polymorphisms i...
Alternative Titles
Full title
Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects
Authors, Artists and Contributors
Author / Creator
ANZgene
Patsopoulos, Nikolaos A
Barcellos, Lisa F
Hintzen, Rogier Q
Schaefer, Catherine
van Duijn, Cornelia M
Noble, Janelle A
Raj, Towfique
Gourraud, Pierre-Antoine
Stranger, Barbara E
Oksenberg, Jorge
Olsson, Tomas
Taylor, Bruce V
Sawcer, Stephen
Hafler, David A
Carrington, Mary
De Jager, Philip L
de Bakker, Paul I W
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1468592099
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1468592099
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1003926
