Increasing RpoS Expression Causes Cell Death in Borrelia burgdorferi
Increasing RpoS Expression Causes Cell Death in Borrelia burgdorferi
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Author / Creator
Chen, Linxu , Xu, Qilong , Tu, Jiagang , Ge, Yihe , Liu, Jun and Liang, Fang Ting
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
RpoS, one of the two alternative σ factors in Borrelia burgdorferi, is tightly controlled by multiple regulators and, in turn, determines expression of many critical virulence factors. Here we show that increasing RpoS expression causes cell death. The immediate effect of increasing RpoS expression was to promote bacterial division and as a consequ...
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Full title
Increasing RpoS Expression Causes Cell Death in Borrelia burgdorferi
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TN_cdi_plos_journals_1468609420
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1468609420
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0083276