Co-expression of SERCA isoforms, phospholamban and sarcolipin in human skeletal muscle fibers
Co-expression of SERCA isoforms, phospholamban and sarcolipin in human skeletal muscle fibers
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
Sarcolipin (SLN) and phospholamban (PLN) inhibit the activity of sarco(endo)plasmic reticulum Ca(2+)-ATPases (SERCAs) by reducing their apparent affinity for Ca(2+). A ternary complex between SLN, PLN, and SERCAs results in super-inhibition of SERCA activity. Analysis of skeletal muscle homogenate has limited our current understanding of whether SL...
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Full title
Co-expression of SERCA isoforms, phospholamban and sarcolipin in human skeletal muscle fibers
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TN_cdi_plos_journals_1468609507
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1468609507
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0084304
