Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal...
Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The pathogenesis of splenic marginal zone lymphoma (SMZL) remains largely unknown. Recent high-throughput sequencing studies have identified recurrent mutations in key pathways, most notably NOTCH2 mutations in >25% of patients. These studies are based on small, heterogeneous discovery cohorts, and therefore only captured a fraction of the lesions...
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Full title
Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma
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TN_cdi_plos_journals_1468934817
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1468934817
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0083244
