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Exploring early stages of the chemical unfolding of proteins at the proteome scale

Exploring early stages of the chemical unfolding of proteins at the proteome scale

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1477947642

Exploring early stages of the chemical unfolding of proteins at the proteome scale

About this item

Full title

Exploring early stages of the chemical unfolding of proteins at the proteome scale

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2013-12, Vol.9 (12), p.e1003393-e1003393

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

After decades of using urea as denaturant, the kinetic role of this molecule in the unfolding process is still undefined: does urea actively induce protein unfolding or passively stabilize the unfolded state? By analyzing a set of 30 proteins (representative of all native folds) through extensive molecular dynamics simulations in denaturant (using...

Alternative Titles

Full title

Exploring early stages of the chemical unfolding of proteins at the proteome scale

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1477947642

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1477947642

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1003393

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