Distinct and Site-Specific Phosphorylation of the Retinoblastoma Protein at Serine 612 in Differenti...
Distinct and Site-Specific Phosphorylation of the Retinoblastoma Protein at Serine 612 in Differentiated Cells
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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The retinoblastoma susceptibility protein (pRB) is a phosphoprotein that regulates cell cycle progression at the G1/S transition. In quiescent and early G1 cells, pRB predominantly exists in the active hypophosphorylated form. The cyclin/cyclin-dependent protein kinase complexes phosphorylate pRB at the late G1 phase to inactivate pRB. This event l...
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Full title
Distinct and Site-Specific Phosphorylation of the Retinoblastoma Protein at Serine 612 in Differentiated Cells
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TN_cdi_plos_journals_1490992576
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1490992576
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0086709
