miR-122 targets pyruvate kinase M2 and affects metabolism of hepatocellular carcinoma
miR-122 targets pyruvate kinase M2 and affects metabolism of hepatocellular carcinoma
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
In contrast to normal differentiated cells that depend on mitochondrial oxidative phosphorylation for energy production, cancer cells have evolved to utilize aerobic glycolysis (Warburg's effect), with benefit of providing intermediates for biomass production. MicroRNA-122 (miR-122) is highly expressed in normal liver tissue regulating a wide varie...
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Full title
miR-122 targets pyruvate kinase M2 and affects metabolism of hepatocellular carcinoma
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TN_cdi_plos_journals_1491323508
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1491323508
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0086872
