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Cell tropism predicts long-term nucleotide substitution rates of mammalian RNA viruses

Cell tropism predicts long-term nucleotide substitution rates of mammalian RNA viruses

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1498393093

Cell tropism predicts long-term nucleotide substitution rates of mammalian RNA viruses

About this item

Full title

Cell tropism predicts long-term nucleotide substitution rates of mammalian RNA viruses

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2014-01, Vol.10 (1), p.e1003838-e1003838

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The high rates of RNA virus evolution are generally attributed to replication with error-prone RNA-dependent RNA polymerases. However, these long-term nucleotide substitution rates span three orders of magnitude and do not correlate well with mutation rates or selection pressures. This substitution rate variation may be explained by differences in...

Alternative Titles

Full title

Cell tropism predicts long-term nucleotide substitution rates of mammalian RNA viruses

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1498393093

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1498393093

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1003838

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