Synthetic LPETG-containing peptide incorporation in the Staphylococcus aureus cell-wall in a sortase...
Synthetic LPETG-containing peptide incorporation in the Staphylococcus aureus cell-wall in a sortase A- and growth phase-dependent manner
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The majority of Staphylococcus aureus virulence- and colonization-associated surface proteins contain a pentapeptide recognition motif (LPXTG). This motif can be recognized and cleaved by sortase A (SrtA) which is a membrane-bound transpeptidase. After cleavage these proteins are covalently incorporated into the peptidoglycan. Therefore, SrtA plays...
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Full title
Synthetic LPETG-containing peptide incorporation in the Staphylococcus aureus cell-wall in a sortase A- and growth phase-dependent manner
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TN_cdi_plos_journals_1500409764
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1500409764
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0089260
