IL-10-producing B cells are induced early in HIV-1 infection and suppress HIV-1-specific T cell resp...
IL-10-producing B cells are induced early in HIV-1 infection and suppress HIV-1-specific T cell responses
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Author / Creator
Liu, Jun , Zhan, Wei , Kim, Connie J , Clayton, Kiera , Zhao, Hanqi , Lee, Erika , Cao, Jin Chao , Ziegler, Blake , Gregor, Alexander , Yue, Feng Yun , Huibner, Sanja , MacParland, Sonya , Schwartz, Jordan , Song, Hai Han , Benko, Erika , Gyenes, Gabor , Kovacs, Colin , Kaul, Rupert and Ostrowski, Mario
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
A rare subset of IL-10-producing B cells, named regulatory B cells (Bregs), suppresses adaptive immune responses and inflammation in mice. In this study, we examined the role of IL-10-producing B cells in HIV-1 infection. Compared to uninfected controls, IL-10-producing B cell frequencies were elevated in both blood and sigmoid colon during the ear...
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Full title
IL-10-producing B cells are induced early in HIV-1 infection and suppress HIV-1-specific T cell responses
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Record Identifier
TN_cdi_plos_journals_1500940067
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1500940067
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0089236
