Log in to save to my catalogue

Temsirolimus inhibits proliferation and migration in retinal pigment epithelial and endothelial cell...

Temsirolimus inhibits proliferation and migration in retinal pigment epithelial and endothelial cell...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1502642401

Temsirolimus inhibits proliferation and migration in retinal pigment epithelial and endothelial cells via mTOR inhibition and decreases VEGF and PDGF expression

About this item

Full title

Temsirolimus inhibits proliferation and migration in retinal pigment epithelial and endothelial cells via mTOR inhibition and decreases VEGF and PDGF expression

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-02, Vol.9 (2), p.e88203

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Due to their high prevalence, retinal vascular diseases including age related macular degeneration (AMD), retinal vein occlusions (RVO), diabetic retinopathy (DR) and diabetic macular edema have been major therapeutic targets over the last years. The pathogenesis of these diseases is complex and yet not fully understood. However, increased prolifer...

Alternative Titles

Full title

Temsirolimus inhibits proliferation and migration in retinal pigment epithelial and endothelial cells via mTOR inhibition and decreases VEGF and PDGF expression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1502642401

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1502642401

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0088203

How to access this item