Temsirolimus inhibits proliferation and migration in retinal pigment epithelial and endothelial cell...
Temsirolimus inhibits proliferation and migration in retinal pigment epithelial and endothelial cells via mTOR inhibition and decreases VEGF and PDGF expression
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Due to their high prevalence, retinal vascular diseases including age related macular degeneration (AMD), retinal vein occlusions (RVO), diabetic retinopathy (DR) and diabetic macular edema have been major therapeutic targets over the last years. The pathogenesis of these diseases is complex and yet not fully understood. However, increased prolifer...
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Full title
Temsirolimus inhibits proliferation and migration in retinal pigment epithelial and endothelial cells via mTOR inhibition and decreases VEGF and PDGF expression
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TN_cdi_plos_journals_1502642401
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1502642401
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0088203