NSUN4 is a dual function mitochondrial protein required for both methylation of 12S rRNA and coordin...
NSUN4 is a dual function mitochondrial protein required for both methylation of 12S rRNA and coordination of mitoribosomal assembly
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Biogenesis of mammalian mitochondrial ribosomes requires a concerted maturation of both the small (SSU) and large subunit (LSU). We demonstrate here that the m(5)C methyltransferase NSUN4, which forms a complex with MTERF4, is essential in mitochondrial ribosomal biogenesis as mitochondrial translation is abolished in conditional Nsun4 mouse knocko...
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NSUN4 is a dual function mitochondrial protein required for both methylation of 12S rRNA and coordination of mitoribosomal assembly
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TN_cdi_plos_journals_1507833679
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1507833679
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1004110
