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A combination of activation and repression by a colinear Hox code controls forelimb-restricted expre...

A combination of activation and repression by a colinear Hox code controls forelimb-restricted expre...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1516767782

A combination of activation and repression by a colinear Hox code controls forelimb-restricted expression of Tbx5 and reveals Hox protein specificity

About this item

Full title

A combination of activation and repression by a colinear Hox code controls forelimb-restricted expression of Tbx5 and reveals Hox protein specificity

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2014-03, Vol.10 (3), p.e1004245-e1004245

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Tight control over gene expression is essential for precision in embryonic development and acquisition of the regulatory elements responsible is the predominant driver for evolution of new structures. Tbx5 and Tbx4, two genes expressed in forelimb and hindlimb-forming regions respectively, play crucial roles in the initiation of limb outgrowth. Evo...

Alternative Titles

Full title

A combination of activation and repression by a colinear Hox code controls forelimb-restricted expression of Tbx5 and reveals Hox protein specificity

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1516767782

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1516767782

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1004245

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