Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key d...
Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Many critical events in the Plasmodium life cycle rely on the controlled release of Ca²⁺ from intracellular stores to activate stage-specific Ca²⁺-dependent protein kinases. Using the motility of Plasmodium berghei ookinetes as a signalling paradigm, we show that the cyclic guanosine monophosphate (cGMP)-dependent protein kinase, PKG, maintains the...
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Full title
Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites
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TN_cdi_plos_journals_1516768162
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1516768162
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.1001806
