Direct evidence for pitavastatin induced chromatin structure change in the KLF4 gene in endothelial...
Direct evidence for pitavastatin induced chromatin structure change in the KLF4 gene in endothelial cells
About this item
Full title
Author / Creator
Maejima, Takashi , Inoue, Tsuyoshi , Kanki, Yasuharu , Kohro, Takahide , Li, Guoliang , Ohta, Yoshihiro , Kimura, Hiroshi , Kobayashi, Mika , Taguchi, Akashi , Tsutsumi, Shuichi , Iwanari, Hiroko , Yamamoto, Shogo , Aruga, Hirofumi , Dong, Shoulian , Stevens, Junko F , Poh, Huay Mei , Yamamoto, Kazuki , Kawamura, Takeshi , Mimura, Imari , Suehiro, Jun-ichi , Sugiyama, Akira , Kaneki, Kiyomi , Shibata, Haruki , Yoshinaka, Yasunobu , Doi, Takeshi , Asanuma, Akimune , Tanabe, Sohei , Tanaka, Toshiya , Minami, Takashi , Hamakubo, Takao , Sakai, Juro , Nozaki, Naohito , Aburatani, Hiroyuki , Nangaku, Masaomi , Ruan, Xiaoan , Tanabe, Hideyuki , Ruan, Yijun , Ihara, Sigeo , Endo, Akira , Kodama, Tatsuhiko and Wada, Youichiro
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Statins exert atheroprotective effects through the induction of specific transcriptional factors in multiple organs. In endothelial cells, statin-dependent atheroprotective gene up-regulation is mediated by Kruppel-like factor (KLF) family transcription factors. To dissect the mechanism of gene regulation, we sought to determine molecular targets b...
Alternative Titles
Full title
Direct evidence for pitavastatin induced chromatin structure change in the KLF4 gene in endothelial cells
Authors, Artists and Contributors
Author / Creator
Inoue, Tsuyoshi
Kanki, Yasuharu
Kohro, Takahide
Li, Guoliang
Ohta, Yoshihiro
Kimura, Hiroshi
Kobayashi, Mika
Taguchi, Akashi
Tsutsumi, Shuichi
Iwanari, Hiroko
Yamamoto, Shogo
Aruga, Hirofumi
Dong, Shoulian
Stevens, Junko F
Poh, Huay Mei
Yamamoto, Kazuki
Kawamura, Takeshi
Mimura, Imari
Suehiro, Jun-ichi
Sugiyama, Akira
Kaneki, Kiyomi
Shibata, Haruki
Yoshinaka, Yasunobu
Doi, Takeshi
Asanuma, Akimune
Tanabe, Sohei
Tanaka, Toshiya
Minami, Takashi
Hamakubo, Takao
Sakai, Juro
Nozaki, Naohito
Aburatani, Hiroyuki
Nangaku, Masaomi
Ruan, Xiaoan
Tanabe, Hideyuki
Ruan, Yijun
Ihara, Sigeo
Endo, Akira
Kodama, Tatsuhiko
Wada, Youichiro
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1520987894
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1520987894
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0096005
