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Maternal separation enhances conditioned fear and decreases the mRNA levels of the neurotensin recep...

Maternal separation enhances conditioned fear and decreases the mRNA levels of the neurotensin recep...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1524876271

Maternal separation enhances conditioned fear and decreases the mRNA levels of the neurotensin receptor 1 gene with hypermethylation of this gene in the rat amygdala

About this item

Full title

Maternal separation enhances conditioned fear and decreases the mRNA levels of the neurotensin receptor 1 gene with hypermethylation of this gene in the rat amygdala

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-05, Vol.9 (5), p.e97421-e97421

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Stress during postnatal development is associated with an increased risk for depression, anxiety disorders, and substance abuse later in life, almost as if mental illness is able to be programed by early life stressors. Recent studies suggest that such "programmed" effects can be caused by epigenetic regulation. With respect to conditioned fear, pr...

Alternative Titles

Full title

Maternal separation enhances conditioned fear and decreases the mRNA levels of the neurotensin receptor 1 gene with hypermethylation of this gene in the rat amygdala

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1524876271

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1524876271

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0097421

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