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Alveolar macrophages are essential for protection from respiratory failure and associated morbidity...

Alveolar macrophages are essential for protection from respiratory failure and associated morbidity...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1525297243

Alveolar macrophages are essential for protection from respiratory failure and associated morbidity following influenza virus infection

About this item

Full title

Alveolar macrophages are essential for protection from respiratory failure and associated morbidity following influenza virus infection

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2014-04, Vol.10 (4), p.e1004053-e1004053

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Alveolar macrophages (AM) are critical for defense against bacterial and fungal infections. However, a definitive role of AM in viral infections remains unclear. We here report that AM play a key role in survival to influenza and vaccinia virus infection by maintaining lung function and thereby protecting from asphyxiation. Absence of AM in GM-CSF-...

Alternative Titles

Full title

Alveolar macrophages are essential for protection from respiratory failure and associated morbidity following influenza virus infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1525297243

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1525297243

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1004053

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