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Statistical power to detect genetic (co)variance of complex traits using SNP data in unrelated sampl...

Statistical power to detect genetic (co)variance of complex traits using SNP data in unrelated sampl...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1525303940

Statistical power to detect genetic (co)variance of complex traits using SNP data in unrelated samples

About this item

Full title

Statistical power to detect genetic (co)variance of complex traits using SNP data in unrelated samples

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2014-04, Vol.10 (4), p.e1004269-e1004269

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

We have recently developed analysis methods (GREML) to estimate the genetic variance of a complex trait/disease and the genetic correlation between two complex traits/diseases using genome-wide single nucleotide polymorphism (SNP) data in unrelated individuals. Here we use analytical derivations and simulations to quantify the sampling variance of...

Alternative Titles

Full title

Statistical power to detect genetic (co)variance of complex traits using SNP data in unrelated samples

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1525303940

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1525303940

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1004269

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