Statistical power to detect genetic (co)variance of complex traits using SNP data in unrelated sampl...
Statistical power to detect genetic (co)variance of complex traits using SNP data in unrelated samples
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
We have recently developed analysis methods (GREML) to estimate the genetic variance of a complex trait/disease and the genetic correlation between two complex traits/diseases using genome-wide single nucleotide polymorphism (SNP) data in unrelated individuals. Here we use analytical derivations and simulations to quantify the sampling variance of...
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Full title
Statistical power to detect genetic (co)variance of complex traits using SNP data in unrelated samples
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TN_cdi_plos_journals_1525303940
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1525303940
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1004269