Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation
Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation
About this item
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Author / Creator
Fielding, Ceri A , Aicheler, Rebecca , Stanton, Richard J , Wang, Eddie C Y , Han, Song , Seirafian, Sepehr , Davies, James , McSharry, Brian P , Weekes, Michael P , Antrobus, P Robin , Prod'homme, Virginie , Blanchet, Fabien P , Sugrue, Daniel , Cuff, Simone , Roberts, Dawn , Davison, Andrew J , Lehner, Paul J , Wilkinson, Gavin W G and Tomasec, Peter
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
NKG2D plays a major role in controlling immune responses through the regulation of natural killer (NK) cells, αβ and γδ T-cell function. This activating receptor recognizes eight distinct ligands (the MHC Class I polypeptide-related sequences (MIC) A andB, and UL16-binding proteins (ULBP)1-6) induced by cellular stress to promote recognition cells...
Alternative Titles
Full title
Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation
Authors, Artists and Contributors
Author / Creator
Aicheler, Rebecca
Stanton, Richard J
Wang, Eddie C Y
Han, Song
Seirafian, Sepehr
Davies, James
McSharry, Brian P
Weekes, Michael P
Antrobus, P Robin
Prod'homme, Virginie
Blanchet, Fabien P
Sugrue, Daniel
Cuff, Simone
Roberts, Dawn
Davison, Andrew J
Lehner, Paul J
Wilkinson, Gavin W G
Tomasec, Peter
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1536044911
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1536044911
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1004058
