HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors...
HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Innate immune sensing of viral infection results in type I interferon (IFN) production and inflammasome activation. Type I IFNs, primarily IFN-α and IFN-β, are produced by all cell types upon virus infection and promote an antiviral state in surrounding cells by inducing the expression of IFN-stimulated genes. Type I IFN production is mediated by T...
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Full title
HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon
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TN_cdi_plos_journals_1536045170
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1536045170
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1004082
