Inhibition of CSF-1R supports T-cell mediated melanoma therapy
Inhibition of CSF-1R supports T-cell mediated melanoma therapy
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Tumor associated macrophages (TAM) can promote angiogenesis, invasiveness and immunosuppression. The cytokine CSF-1 (or M-CSF) is an important factor of TAM recruitment and differentiation and several pharmacological agents targeting the CSF-1 receptor (CSF-1R) have been developed to regulate TAM in solid cancers. We show that the kinase inhibitor...
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Full title
Inhibition of CSF-1R supports T-cell mediated melanoma therapy
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TN_cdi_plos_journals_1552644584
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1552644584
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0104230
