Detection of MPLW515L/K Mutations and Determination of Allele Frequencies with a Single-Tube PCR Ass...
Detection of MPLW515L/K Mutations and Determination of Allele Frequencies with a Single-Tube PCR Assay
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
A gain-of-function mutation in the myeloproliferative leukemia virus (MPL) gene, which encodes the thrombopoietin receptor, has been identified in patients with essential thrombocythemia and primary myelofibrosis, subgroups of classic myeloproliferative neoplasms (MPNs). The presence of MPL gene mutations is a critical diagnostic criterion for thes...
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Full title
Detection of MPLW515L/K Mutations and Determination of Allele Frequencies with a Single-Tube PCR Assay
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TN_cdi_plos_journals_1555283572
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1555283572
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0104958
