Comparison of the anti-prion mechanism of four different anti-prion compounds, anti-PrP monoclonal a...
Comparison of the anti-prion mechanism of four different anti-prion compounds, anti-PrP monoclonal antibody 44B1, pentosan polysulfate, chlorpromazine, and U18666A, in prion-infected mouse neuroblastoma cells
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Molecules that inhibit the formation of an abnormal isoform of prion protein (PrP(Sc)) in prion-infected cells are candidate therapeutic agents for prion diseases. Understanding how these molecules inhibit PrP(Sc) formation provides logical basis for proper evaluation of their therapeutic potential. In this study, we extensively analyzed the effect...
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Full title
Comparison of the anti-prion mechanism of four different anti-prion compounds, anti-PrP monoclonal antibody 44B1, pentosan polysulfate, chlorpromazine, and U18666A, in prion-infected mouse neuroblastoma cells
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TN_cdi_plos_journals_1559041476
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1559041476
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0106516
