64Cu-DOTA-anti-CTLA-4 mAb enabled PET visualization of CTLA-4 on the T-cell infiltrating tumor tissu...
64Cu-DOTA-anti-CTLA-4 mAb enabled PET visualization of CTLA-4 on the T-cell infiltrating tumor tissues
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) targeted therapy by anti-CTLA-4 monoclonal antibody (mAb) is highly effective in cancer patients. However, it is extremely expensive and potentially produces autoimmune-related adverse effects. Therefore, the development of a method to evaluate CTLA-4 expression prior to CTLA-4-targeted therapy i...
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Full title
64Cu-DOTA-anti-CTLA-4 mAb enabled PET visualization of CTLA-4 on the T-cell infiltrating tumor tissues
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TN_cdi_plos_journals_1619509862
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1619509862
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0109866