NIAM-deficient mice are predisposed to the development of proliferative lesions including B-cell lym...
NIAM-deficient mice are predisposed to the development of proliferative lesions including B-cell lymphomas
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Nuclear Interactor of ARF and Mdm2 (NIAM, gene designation Tbrg1) is a largely unstudied inhibitor of cell proliferation that helps maintain chromosomal stability. It is a novel activator of the ARF-Mdm2-Tip60-p53 tumor suppressor pathway as well as other undefined pathways important for genome maintenance. To examine its predicted role as a tumor...
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Full title
NIAM-deficient mice are predisposed to the development of proliferative lesions including B-cell lymphomas
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TN_cdi_plos_journals_1624943944
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1624943944
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0112126
