Anti-CD45 radioimmunotherapy with 90Y but not 177Lu is effective treatment in a syngeneic murine leu...
Anti-CD45 radioimmunotherapy with 90Y but not 177Lu is effective treatment in a syngeneic murine leukemia model
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Radioimmunotherapy (RIT) for treatment of hematologic malignancies has primarily employed monoclonal antibodies (Ab) labeled with 131I or 90Y which have limitations, and alternative radionuclides are needed to facilitate wider adoption of RIT. We therefore compared the relative therapeutic efficacy and toxicity of anti-CD45 RIT employing 90Y and 17...
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Full title
Anti-CD45 radioimmunotherapy with 90Y but not 177Lu is effective treatment in a syngeneic murine leukemia model
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TN_cdi_plos_journals_1629597192
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1629597192
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0113601
