Dynamic scenario of membrane binding process of kalata b1
Dynamic scenario of membrane binding process of kalata b1
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Kalata B1 (kB1), a cyclotide that has been used in medical applications, displays cytotoxicity related to membrane binding and oligomerization. Our molecular dynamics simulation results demonstrate that Trp19 in loop 5 of both monomeric and tetrameric kB1 is a key residue for initial anchoring in the membrane binding process. This residue also faci...
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Full title
Dynamic scenario of membrane binding process of kalata b1
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TN_cdi_plos_journals_1630367019
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1630367019
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0114473
