mTORC2 is required for rit-mediated oxidative stress resistance
mTORC2 is required for rit-mediated oxidative stress resistance
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Rit, a member of the Ras family of GTPases, has been shown to promote cell survival in response to oxidative stress, in part by directing an evolutionarily conserved p38 MAPK-Akt survival cascade. Aberrant Rit signaling has recently been implicated as a driver mutation in human cancer, adding importance to the characterization of critical Rit effec...
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Full title
mTORC2 is required for rit-mediated oxidative stress resistance
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TN_cdi_plos_journals_1639492197
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1639492197
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0115602
