Dynamic Growth and Shrinkage Govern the pH Dependence of RecA Filament Stability
Dynamic Growth and Shrinkage Govern the pH Dependence of RecA Filament Stability
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United States: Public Library of Science
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English
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United States: Public Library of Science
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RecA proteins form a long stable filament on a single-stranded DNA and catalyze strand exchange reaction. The stability of RecA filament changes dramatically with pH, yet its detailed mechanism is not known. Here, using a single molecule assay, we determined the binding and dissociation rates of RecA monomers at the filament ends at various pH. The...
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Dynamic Growth and Shrinkage Govern the pH Dependence of RecA Filament Stability
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TN_cdi_plos_journals_1658107118
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1658107118
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0115611